Is a rare genetic hair disorder characterized by a beaded appearance of the hair shaft. It is an autosomal dominant condition, meaning that an affected individual only needs to inherit one copy of the mutated gene from one parent to display the symptoms.


 by mutations in the hair-specific keratin genes, particularly the KRT81, KRT83, and KRT86 genes, which encode proteins essential for the formation of hair structure.


is the periodic narrowing of the hair shaft resulting in a series of constrictions that resemble beads or nodes along the hair. This gives the hair a fragile and brittle quality, making it prone to breakage and hair loss. The severity of the condition can vary widely among individuals, with some experiencing mild symptoms and others having more extensive involvement.


  • Clinical Evaluation: A dermatologist or healthcare provider will examine the affected individual's hair and scalp. They will look for the characteristic features of monilethrix, which include hair shafts with beaded or nodular constrictions. They will also assess the pattern and distribution of hair loss and any associated symptoms.
  • Microscopic Examination: A hair sample may be taken and examined under a microscope. This can reveal the distinctive beading pattern of the hair shaft. Microscopic analysis helps confirm the diagnosis and differentiate monilethrix from other hair disorders with similar features.
  • Genetic Testing: Genetic testing can confirm the presence of mutations in the KRT81, KRT83, or KRT86 genes associated with monilethrix. This is typically done through DNA analysis, which may involve a blood sample or a cheek swab. Identifying these specific gene mutations helps confirm the diagnosis and can also provide information about the inheritance pattern.
  • Family History: Monilethrix is often inherited in an autosomal dominant manner, meaning that a person with the condition has a 50% chance of passing it on to their offspring. A thorough family history can provide additional clues about the genetic basis of the disorder.


  1. Lycopodium: This remedy is often prescribed for hair loss associated with hormonal imbalances, especially in cases where hair loss is more prominent on the sides of the head while the crown remains relatively unaffected. It can be beneficial for hair fall due to stress or illness.
  2. Silicea: Silicea is used for hair loss when the hair is dry, brittle, and falls out easily. It can be helpful in cases where there is a history of slow hair growth and weak nails. Silicea is also known to improve the overall health of hair and nails.
  3. Phosphorus: Phosphorus is recommended for hair loss caused by emotional stress or grief. It is also indicated when hair loss occurs in patches and there is a tendency for hair to break or fall out easily.
  4. Sepia: Sepia is often prescribed for hair loss after childbirth or hormonal changes, as well as in cases of hair loss related to stress or emotional issues. It can be particularly effective for women experiencing hair loss during or after pregnancy.
  5. Natrum muriaticum: This remedy is used for hair loss associated with a dry, itchy scalp and dandruff. It can also be beneficial for hair loss due to hormonal imbalances, especially in women.
  6. Arnica: Arnica is sometimes recommended for hair loss caused by physical trauma or injury to the scalp. It can also promote hair growth by improving blood circulation to the hair follicles.
  7. Graphites: Graphites is indicated for hair loss with dry, rough, and itchy skin on the scalp. It can be beneficial when hair falls out in patches or when the scalp is prone to infections.