( Chorioadenoma Destruens):- Invasive mole comprises about 15 percent of all GTN.
The prominent features of this type of mole are invasive and destructive potentialities. Invasive mole shows abnormal penetration through the muscle layers of the uterus. The uterine wall may be perforated at multiple areas showing purple, fungating growth with massive intraperitoneal hemorrhage. The neoplasm may invade the pelvic blood vessels and metastasizes to vagina or distant sites as like those in choriocarcinoma.
- On laparotomy:
(a) Perforation of the uterus through which purple fungating growth is visible.
- Histology— There is penetration of the uterine wall by the hyperplastic trophoblastic cells which still retain villus structures. There is no evidence of muscle necrosis. The materials for uterine curettage are often deceptive as the lesion may be deep inside the myometrium.
- Persistent high level of urinary or serum hCG.
The Homeopathic medicine that can be thought of use are: -