Fibrous dysplasia is a rare bone disorder characterized by the abnormal growth and development of fibrous tissue within the bone. It is considered a non-inherited condition, meaning it typically occurs sporadically and is not passed down through families.

In fibrous dysplasia, the normal bone tissue is gradually replaced by fibrous tissue, which can weaken the affected bone and lead to various symptoms. While fibrous dysplasia can occur in any bone, it most commonly affects the long bones of the legs and arms, as well as the skull and facial bones.

There are three main types of fibrous dysplasia:

  1. Monostotic Fibrous Dysplasia: This type involves a single bone and is the most common form. It usually manifests in childhood or adolescence and may cause bone pain, deformity, or fractures in severe cases.
  2. Polyostotic Fibrous Dysplasia: Polyostotic fibrous dysplasia affects multiple bones and may occur in combination with other conditions, such as endocrine abnormalities in a condition called McCune-Albright syndrome. This type tends to be more severe, with a higher risk of fractures and skeletal deformities.
  3. McCune-Albright Syndrome: This rare condition combines polyostotic fibrous dysplasia with other features, including skin pigmentation (cafe-au-lait spots) and endocrine gland abnormalities, such as early puberty (precocious puberty) or hormone imbalances.


The exact cause of fibrous dysplasia is not fully understood, but it is thought to result from a genetic mutation that affects the normal development and maturation of bone-forming cells. This mutation occurs spontaneously and is not inherited in most cases.


Diagnosis of fibrous dysplasia involves a combination of clinical evaluation, imaging studies (such as X-rays, CT scans, or MRI), and sometimes a biopsy to examine the tissue microscopically. Biopsies are usually reserved for atypical cases or when other conditions need to be ruled out.


Calcarea phosphorica: This remedy is often used for conditions involving weak or brittle bones, slow healing fractures, and bone deformities. It may be considered for individuals with fibrous dysplasia experiencing bone pain and deformity.

Silicea: Silicea is known for its effects on bone and connective tissue. It may be prescribed for conditions involving slow healing fractures, bone deformities, or recurrent infections related to the bones. It is sometimes used as a constitutional remedy to support overall bone health.

Phosphorus: Phosphorus is known to have an affinity for the bones and may be considered for conditions involving bone pain, weakness, and deformities. It may also be useful for individuals experiencing increased thirst and a tendency toward bleeding.

Symphytum officinale: Commonly known as Comfrey, Symphytum is used for promoting bone healing and relieving bone pain. It may be considered for individuals with fibrous dysplasia experiencing bone fractures or trauma.

Ruta graveolens: Ruta is often used for conditions involving strained or injured tendons, ligaments, and bones. It may be prescribed for individuals experiencing pain, stiffness, or weakness in the bones or joints affected by fibrous dysplasia.